CORDIS Project
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This project explores the influence of reverse causal effects across biological scales, focusing on human stem cells and early zebrafish embryos. It aims to develop advanced imaging methods to quantify gene expression and cellular behavior, potentially transforming biology and medicine.
The central dogma in biology often invokes a bottom-up picture of life.
However, at different biological scales, new properties in form and function arise that have a superseding causal impact on the behaviour of the lower-scale components from which these new properties emerge.
These top-down or reverse scale-crossing effects must be taken into account in order to make predictions about spatiotemporally controlled single-cell fates, activities, levels of gene expression, or the functional outco…
UNIVERSITAT ZURICH
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