CORDIS Project
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This research explores the neuroendocrine control of fertility by studying the interactions of specific neuropeptides in the hypothalamus. It aims to clarify the roles of kisspeptins, neurokinin B, and dynorphin in regulating hormone secretion linked to reproductive health.
The function of the hypothalamic-pituitary-gonadal (HPG) axis is mastered by the hypothalamic neuronal population producing gonadotropin-releasing hormone (GnRH), which regulates LH and FSH secretion by the pituitary.
Perturbations of fertility, e.g., in polycystic ovarian syndrome (PCOS) and hypogonadism associated with metabolic disorders, are related to functional alterations in the neuronal networks controlling pulsatile GnRH secretion.
Recently, a neuronal population in the hypothalamic arc…
UNIVERSIDAD DE CORDOBA
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