CORDIS Project
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This project develops a second-generation biobank of mouse tumor organoids for colorectal cancer research. It aims to create advanced models for studying immunotherapies and to facilitate collaboration with pharmaceutical companies for drug development.
Colorectal cancer (CRC) is one of the leading causes of death by cancer, which is largely associated to metastatic spread of the disease.
Progress to develop efficient therapies, including immunotherapies, for patients with metastatic CRC has been hampered by the lack of preclinical models to study late stage CRC in an immunocompetent background.
We have developed the first genetic mouse model of advanced CRC in immunocompetent mice.
This model is based in a biobank of mouse tumor organoids (MT…
FUNDACIO INSTITUT DE RECERCA BIOMEDICA (IRB BARCELONA)
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