CORDIS Project
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This project aims to explore the role of upper motor neuron degeneration in Amyotrophic Lateral Sclerosis (ALS) to develop new therapeutic strategies. It focuses on understanding how this specific neuronal loss contributes to the disease's progression.
Amyotrophic Lateral Sclerosis (ALS) is the most common adult-onset neurodegenerative disease of the motor system, with a prevalence of 2-3/100 000.
In spite of intensive research efforts, ALS remains an incurable disease and presents with a very severe prognosis, leading to patient death within 2 to 5 years following diagnosis.At the cellular level, ALS is characterized by the combined degeneration of both upper motor neurons (UMN, or corticospinal motor neurons) whose cell bodies are located in…
INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
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France, Strasbourg
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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