CORDIS Project
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This project investigates the role of dopamine in the basal ganglia during the automation of action sequences. It aims to understand how different regions communicate and how dysregulation may lead to compulsive behaviors, using advanced monitoring techniques in animal models.
The basal ganglia consist of a set of neuroanatomical structures that participate in the representation and execution of action sequences.
Dopamine neurotransmission in the striatum, the main input nucleus of the basal ganglia, is a fundamental mechanism involved in learning and regulation of such actions.
The striatum has multiple functional units, where the limbic striatum is thought to mediate motivational aspects of actions (e.g., goal-directedness) and the sensorimotor striatum their automa…
ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM
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