CORDIS Project
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This project focuses on alternative splicing, a process that allows a single gene to produce multiple mRNA variants, thereby increasing genetic complexity. By employing a high-throughput approach, the project aims to identify significant alternative splicing events in various biological contexts, particularly in brain…
A major mystery of the genome age is why complex and simple organisms all have a similar number of genes.
My specialism is in ‘Alternative Splicing’ which is the means by which different products can be made from a single gene by differential incorporation of regions of pre-mRNA.
Alternative splicing is therefore a mechanism to increase gene complexity in complex organisms like man and in complex tissues like the brain.
Alternative splicing has since been shown to be a pervasive mechanism crucia…
UNIVERSITY OF NEWCASTLE UPON TYNE
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