CORDIS Project
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This project aims to restore neuronal network activity in the cerebral cortex after injury using human-specific hydrogels and 3D bioprinting techniques. By integrating cortical brain organoids into damaged areas, it seeks to enhance brain plasticity and improve neurological function.
Brain injuries affecting the cerebral cortex result in devastating neurologic deficits from irreversible loss of neurons and still do not have any therapeutic option.
The only possible treatment for these conditions would be the reconstruction of the lost neuronal circuits which could be achieved, in principle, by stem cell therapy.
However, when stem cells are engrafted they only provide trophic effect and are incapable of substantial tissue replacement and rewiring the damaged tissue.
With th…
UNIVERSITA DEGLI STUDI DI PADOVA
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