CORDIS Project
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This project investigates the role of blood vessel cells in the progression of non-alcoholic steato-hepatitis (NASH) to liver cancer. By using advanced imaging and molecular techniques, it aims to characterize the vascular changes in the liver and gut, identify key molecular mechanisms, and explore potential therapeuti…
Non-alcoholic steato-hepatitis (NASH) is a major risk factor for hepatocellular carcinoma (HCC), the 6th most common cause of cancer-related death worldwide.
The transition among different NASH stages to HCC stems from the complex interaction of multiple factors, including gut-liver axis modifications and a progressive dis-architecture of the liver parenchyma.The central role of endothelial cells in regulating the metabolic crosstalk along the gut-liver axis and in shaping the spatial organizati…
UNIVERSITA VITA-SALUTE SAN RAFFAELE
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