CORDIS Project
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This project focuses on understanding the mechanisms of the condensin protein complex, which is essential for the organization of chromosomes during cell division. By employing advanced imaging and biochemical techniques, it aims to reveal how condensin interacts with DNA to shape chromosome structures.
Chromosomes undergo dramatic changes in their three-dimensional organisation during all aspects of genome function, ranging from the regulation of gene expression during cellular differentiation to chromosome duplication and partitioning over the course of a cell division cycle.
The multi-subunit condensin protein complex plays major roles for these changes in DNA topology.
Despite its fundamental importance, the mechanisms of condensin’s action are not understood.Here, I propose a comprehensive…
JULIUS-MAXIMILIANS-UNIVERSITAT WURZBURG
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