CORDIS Project
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This project aims to understand the molecular mechanisms behind the folding of conotoxins, complex peptides from marine cone snails, which are valuable for pharmacology. It seeks to develop efficient production systems for these peptides to enhance their therapeutic applications.
Predatory marine cone snails use extraordinarily complex venoms to capture prey.
Most of the ~500,000 biologically active venom components are small, disulfide-rich peptides called conotoxins.
They target receptors and ion channels of the nervous system with remarkable potency and specificity.
Due to their enormous diversity and target specificity, conotoxins have become invaluable tools in molecular pharmacology and as therapeutic agents.
However, their chemical synthesis is hampered by multipl…
KOBENHAVNS UNIVERSITET
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