CORDIS Project
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This project investigates the assembly of protein complexes in cells, aiming to understand the order and structure of assembly intermediates. By combining systems biology with structural biology, it seeks to reveal how protein synthesis is coordinated with complex formation.
Protein complexes are central to many cellular functions but our knowledge of how cells assemble protein complexes remains very sparse.
Biophysical and structural data of assembly intermediates are extremely rare.
Particularly in higher eukaryotes, it has become clear that complex assembly by random collision of subunits cannot cope with the spatial and temporal complexity of the intricate architecture of many cellular machines.
Here I propose to combine systems biology approaches with in situ s…
MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
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