CORDIS Project
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The project aims to unravel the genetic architecture of complex traits using the yeast model organism. By employing advanced genomic technologies, it seeks to identify genetic variants affecting mitochondrial function, providing insights into the genetics of multifactorial diseases.
The vast majority of genetic diseases are complex traits, conditioned by multiple genetic and environmental factors.
Yet our understanding of the genetics underlying such traits in humans remains extremely limited, due largely to the statistical complexity of inferring the effects of allelic variants in a genetically diverse population.
Novel tools for the dissection of the genetic architecture of complex traits, therefore, can be most effectively developed in model organisms, where the contrib…
EUROPEAN MOLECULAR BIOLOGY LABORATORY
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