CORDIS Project
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This project investigates how cell division and polarity are coordinated at the organism level using the Drosophila follicle epithelium. It focuses on the roles of specific mitotic proteins in maintaining epithelial structure and understanding their implications for cancer progression.
Shaping the tissues that make an organism requires a tight control of cell division and mechanisms that spatially distribute signalling cues and adhesive structures within single cells.
Although cell division and polarity have been extensively studied, how these processes are coordinated is largely unknown.The primary goal of this project is to understand the link between regulation of mitotic cell division and the organization of polarity at the organism level.
First, we will use the Drosophila…
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