CORDIS Project
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This project focuses on enhancing the synthesis of small organic molecules through improved catalytic methods. It aims to explore dual catalytic processes that combine organocatalysis and transition metal catalysis to achieve better stereoselectivity, which is vital for pharmaceutical applications.
The stereoselective synthesis of small organic molecules depends on robust catalytic methods.
Despite many advances in enantioselective synthesis, an unsolved challenge in catalysis is the translation of enantioselective catalytic reactions to diastereoselective reactions – where a chiral catalyst controls the outcome of reaction of a chiral substrate.
In this proposal, we seek to investigate this 'double stereodifferentiation' in various organocatalytic reactions, and in transition metal-cataly…
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