CORDIS Project
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This project investigates the genetic factors that contribute to antibiotic resistance in Mycobacterium tuberculosis, particularly focusing on how some bacteria can survive antibiotic treatment despite being genetically sensitive. The goal is to understand the mechanisms behind this persistence to improve tuberculosis…
Mycobacterium tuberculosis (Mtb) is one of about a dozen bacterial species for which some clinical isolates are now resistant to most or all antibiotics (abx) approved for treatment of the infections they cause.
Mechanisms of antimicrobial resistance (AMR) in Mtb deserve study for their potential relevance to AMR in other pathogens; because tuberculosis (TB) is now the leading cause of death from infectious disease; and because drug-resistant TB may be the most prevalent of all drug-resistant ba…
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