CORDIS Project
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This project investigates how sensory neurons maintain their functional identities during aging, focusing on the signaling pathways involved in the expression of light-sensitive proteins in fruit flies. It aims to uncover mechanisms of sensory system aging.
This proposal asks the fundamental question of how complex cells, such as sensory neurons, maintain the functional identities they acquire during terminal differentiation.
It builds on my recent results which showed that in one photoreceptor neuron subtype of fruit fly Drosophila melanogaster, a green-sensitive Rhodopsin6 (Rh6, a G-protein-coupled receptor that detects photons) not only functions in the phototransduction, but also signals to maintain repression of the sister receptor gene, the…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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