CORDIS Project
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COLOSSUS focuses on improving treatment options for patients with RAS mutant colorectal cancer by identifying new disease subtypes and actionable pathways. The project aims to develop personalized therapeutic strategies based on comprehensive data analysis.
Colorectal cancer (CRC) is the third most common cancer in Europe with c. 420,000 cases and 150,000 related deaths in 2012.
Of total CRC cases, it is estimated that approximately 50-55 % harbour RAS mutations.
Current treatment for RAS mutant (mt) metastatic(m) CRC is primarily based on 5-fluoruracil based chemotherapy +/- bevacizumab.
However, there are currently limited treatment options once cancers have become resistant.
Moreover, while therapy optimization strategies in RAS wild-type CRC pa…
Partner organizations (coordinator is shown above), with normalized type and CORDIS activity type. Guests see up to 4 partners.
FUNDACION PRIVADA INSTITUTO DEINVESTIGACION ONCOLOGICA DE VALL-HE
Spain, Barcelona
Type: Research institute
Activity type: Research Organisations
SME: No
Ireland, Dublin
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
United Kingdom, London
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
VLAAMS INSTITUUT BIOTECHNOLOGIE FLANDERS INSTITUTE FOR BIOTECHNOLOGY
Belgium, ZWIJNAARDE - GENT
Type: Research institute
Activity type: Research Organisations
SME: No
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