CORDIS Project
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This project investigates the interactions between intestinal helminths and bacteria, aiming to understand their impact on immune responses and chronic inflammatory diseases. By studying these interactions in both mice and humans, the research seeks to uncover mechanisms that could inform new health strategies.
Throughout evolution both intestinal helminths and commensal bacteria have inhabited our intestines.
This "ménage à trois" situation is likely to have exerted a strong selective pressure on the development of our metabolic and immune systems.
Such pressures remain in developing countries, whilst the eradication of helminths in industrialized countries has shifted this evolutionary balance—possibly underlying the increased development of chronic inflammatory diseases.
We hypothesize that helminth…
ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE
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