CORDIS Project
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This project examines how bacteria and their plasmids co-evolve, focusing on the mechanisms of horizontal gene transfer. By studying environmental factors, it aims to understand the dynamics of bacterial adaptation and community structure.
Horizontal gene transfer (HGT) is a fundamental process of bacterial evolution, accelerating adaptation to novel environments and providing access to new ecological niches.
However, two of the three mechanisms of HGT, transduction and conjugation, both rely on semi-autonomous vectors (lysogenic phages and conjugative plasmids, respectively), creating the potential for coadaptation between microbe and vector. I here focus on conjugative plasmids.
These encode their own replication and transfer, a…
THE UNIVERSITY OF SHEFFIELD
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United Kingdom, York North Yorkshire
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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