CORDIS Project
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This project focuses on the fidelity of chromosome segregation during cell division, investigating how specific proteins and modifications guide this process. The research aims to enhance understanding of mitosis and its implications for genomic stability and cancer.
During the human lifetime 10000 trillion cell divisions take place to ensure tissue homeostasis and several vital functions in the organism.
Mitosis is the process that ensures that dividing cells preserve the chromosome number of their progenitors, while deviation from this, a condition known as aneuploidy, represents the most common feature in human cancers.
Here we will test two original concepts with strong implications for chromosome segregation fidelity.
The first concept is based on the “…
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