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CoDe4Bio aims to revolutionize cancer research by developing dynamic 4D biofabricated models that mimic the tumor microenvironment. Utilizing programmable materials and computational design, the project focuses on understanding how physical cues influence cell behavior and drug efficacy, particularly in chronic lymphoc…
Cancer is a global health burden.
In-vitro pre-clinical models play a key role in fighting this burden by encompassing all the activities prior to clinical trials, from tumor microenvironment reconstruction to drug candidate selection.
However, the frequent failure of promising pre-clinical drug candidates highlights two major drawbacks of these models: (i) the difficult reproduction of the dynamic cancer structure related to numerous physical cues; (ii) their experimental nature that suffers fr…
UNIVERSITA DEGLI STUDI DI PAVIA
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