CORDIS Project
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This project investigates how cytomegalovirus-specific T-cells are maintained and activated during latency. By studying the molecular mechanisms that influence T-cell responses, the research aims to enhance vaccine development for diseases like HIV and cancer, while also exploring the implications for immune system agi…
Cytomegalovirus (CMV) is a ubiquitous herpesvirus, latently persisting in the majority of the adult population worldwide.
In these hosts, CMV-specific memory cells dominate the immune memory compartment.
It follows that CMV-specific T-cells dominate the memory compartment of the majority of the human population worldwide.I propose to define within this project the molecular mechanisms driving the inflation of CMV-specific T-cells.
My central hypothesis is that expression levels of CMV peptides d…
HELMHOLTZ-ZENTRUM FUR INFEKTIONSFORSCHUNG GMBH
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