CORDIS Project
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This project explores the concept of multiple infection units in enteric viruses, particularly human norovirus. It aims to understand how these viruses interact with commensal bacteria and to develop strategies for inhibiting infections through targeted approaches.
The last decade of research in enteric virus infection produced a body of compelling evidences that challenged the paradigm of the single infection unit, where a single virus is able to elicit infection of a target cell.
Instead, observational studies of infection in vivo and in vitro suggest that enteric viruses travel in groups: in vesicles with inverted phosphatidylserine topology or at the surface of commensal bacteria.
It has been proposed that both strategies increase locally the viral mul…
UNIVERSITAET zu LUEBECK
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United States, Ann Arbor
Type: University / higher education
Activity type: Higher or Secondary Education Establishments
SME: No
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