CORDIS Project
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This project examines the relationship between sleep patterns, circadian rhythms, and dementia risk. By utilizing genetic data and accelerometer measurements, it aims to identify how sleep duration and circadian disruptions contribute to the onset of dementia, particularly Alzheimer’s disease.
Changes in sleep patterns are common among people with dementia, however why short (≤6hrs) or long sleep (≥9hrs) duration is less favorable for dementia, remains unknown.
Given that approximately 46% & 44% of variability in sleep duration is explained by genetics, it is pertinent to consider genetic influences when understanding the mechanisms contributing to sleep-related risk for dementia.
In addition to sleep, there is growing interest in the relationship between circadian rhythms, the 24-hou…
KAROLINSKA INSTITUTET
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