CORDIS Project
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This project investigates the mechanisms behind cytotoxic lymphocyte exocytosis, which is vital for immune responses. It aims to identify key proteins involved in this process to enhance understanding of immune disorders linked to cytotoxicity defects.
My PhD experience in the field of immunology focused on deciphering vesicular pathways underlying T cell activation profoundly motivated my move to Dr.
Bryceson’s lab, which offers a unique opportunity to explore cytotoxic lymphocyte (CL) exocytosis in the context of human disease.
Cytotoxic lymphocyte exocytosis is critical for life, with mutations in genes required for cytotoxicity causative of severe, early-onset hyperinflammatory syndromes.
Genetic studies have identified several cytosolic p…
KAROLINSKA INSTITUTET
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