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The CITE project focuses on developing advanced analytical technologies to study how the tumor microenvironment affects drug metabolism and resistance in pancreatic cancer. By utilizing spatial pharmacometabolomics and creating a 3D organotypic culture model, the project aims to enhance understanding of drug efficacy a…
Small molecule anti-cancerSmall molecule anti-cancer therapies generally have a well understood mechanism of action.
Still, they are frequently plagued by poor efficacy and high rates of treatment resistance, especially in the context of pancreatic cancer.
One promising newly recognised route of therapy resistance is intratumoral drug inactivation through members of the tumour microenvironment (TME) such as the tumour-associated microbiome.
With the CITE project, I aim to develop novel analytica…
TECHNISCHE UNIVERSITAET MUENCHEN
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