CORDIS Project
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This project investigates how variations in DNA sequences affect gene expression during embryonic development in fruit flies. By analyzing genetic diversity, it aims to understand the relationship between transcription factors and developmental gene regulation, providing insights into the robustness of embryonic develo…
Embryonic development is very robust:
In the midst of segregating mutations and fluctuating environments, a fertilized egg has the remarkable capacity to give rise to a precisely patterned embryo.
The stereotypic progression of development is driven by tightly regulated programs of gene expression.
However, this deterministic view from genetics is at odds with an emerging view of transcription from genomics as a “noisy” process, variable and changing both within and between individuals.
How vari…
EUROPEAN MOLECULAR BIOLOGY LABORATORY
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