CORDIS Project
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This project investigates the role of the tubulin code in the self-organization of cilia, which are essential for various cellular functions. It aims to understand how post-translational modifications of tubulin affect the assembly and motility of cilia.
This project aims at understanding of the role of the tubulin code for self-organization of complex microtubule based structures.
Cilia turn out to be the ideal structures for the proposed research.A cilium is a sophisticated cellular machine that self-organizes from many protein complexes.
It plays motility, sensory, and signaling roles in most eukaryotic cells, and its malfunction causes pathologies.
The assembly of the cilium requires intraflagellar transport (IFT), a specialized bidirectiona…
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