CORDIS Project
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This project investigates how the organization of chromatin in eukaryotic cells affects gene regulation. By employing advanced techniques, it aims to understand the dynamics of chromatin interactions and their impact on gene expression during development.
Transcriptional regulation of genes in eukaryotic cells requires a complex and highly regulated interplay of chromatin environment, epigenetic status of target sequences and several different transcription factors.
Eukaryotic genomes are tightly packaged within nuclei, yet must be accessible for transcription, replication and repair. A striking correlation exists between chromatin topology and underlying gene activity.
According to the textbook view, chromatin loops bring genes into direct conta…
CENTRE EUROPEEN DE RECHERCHE EN BIOLOGIE ET MEDECINE
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