CORDIS Project
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This project investigates the role of chromatin in genome organization and function, focusing on Lepidoptera and other insects. It aims to understand how variations in chromatin composition influence centromere structure and the three-dimensional arrangement of chromosomes during cell division and evolution.
Chromatin contributes to many important processes ensuring the proper functioning of eukaryotic cells.
In addition, it shapes linear and spatial genome organisation, and specifies chromosomal regions including centromeres that play a key role for chromosome segregation.
Chromatin-associated factors also fold the genome in 3D to enable the transfer of chromosomes during mitosis or to regulate gene expression.
Chromatin composition is however not identical among eukaryotes.
How differences in chro…
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
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