CORDIS Project
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This project explores how non-coding RNAs interact with chromatin regulators to control gene expression during development. It focuses on the Polycomb repressive complex 2 and its role in maintaining gene repression, aiming to clarify the mechanisms behind chromatin modifications.
A great challenge in developmental biology research has been to understand how cell type specific expression programs are orchestrated through regulated access to chromatin.
The interaction between non-coding RNAs and chromatin regulators is emerging as an exciting new research area with the potential to explain how chromatin modifications are targeted.Polycomb repressive complex 2 (PRC2) modifies chromatin to maintain developmental regulator genes specific for other cell types in a repressed st…
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