CORDIS Project
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This project aims to understand the organization of chromatin, the complex of DNA and proteins that regulate gene expression. By studying chromatin types in fruit flies, it seeks to reveal how these structures influence gene regulation and genome partitioning.
Chromatin is the ensemble of genomic DNA and hundreds of structural and regulatory proteins.
Together these proteins govern the gene expression program of a cell.
While biochemical and genetic approaches have tought us much about interactions between individual chromatin proteins, we still lack a “big picture” of chromatin: how is the entire interaction network of chromatin proteins organized?My lab discovered that chromatin in Drosophila consists of a limited number of principal types that part…
STICHTING HET NEDERLANDS KANKER INSTITUUT-ANTONI VAN LEEUWENHOEK ZIEKENHUIS
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