CORDIS Project
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This project explores the molecular mechanisms behind chromatin organization in eukaryotic cells. Using advanced imaging techniques, it aims to understand how architectural proteins influence gene expression and DNA processes within the nucleus.
Chromatin packaging into the nucleus of eukaryotic cells is highly sophisticated.
It not only serves to condense the genomic content into restricted space, but mainly to encode epigenetic traits ensuring temporally controlled and balanced transcription of genes and coordinated DNA replication and repair.
The non-random three-dimensional chromatin architecture including looped structures between genomic control elements relies on the action of architectural proteins.
However, despite increasing i…
UNIVERSITAET ULM
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