CORDIS Project
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This project focuses on improving the selective functionalization of carbon-hydrogen bonds in organic compounds using palladium catalysis. By employing computational studies, it aims to enhance the understanding of site-selectivity in complex substrates, ultimately leading to better design of catalysts and substrates f…
The activation of inert C-H bonds lies at the heart of organic chemistry.
In particular C-H activation using transition metal catalysis has made a profound impact on complex molecule synthesis, but the area remains important for future discovery.
At present the utility of synthetic methods based on C-H activation is hampered by the inherent difficulty of being able to selectively functionalize a single C-H bond in the presence of many others.
Thus the ability to perform predictably site-selectiv…
THE CHANCELLOR, MASTERS AND SCHOLARS OF THE UNIVERSITY OF OXFORD
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