CORDIS Project
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This project examines the role of the vagus nerve in regulating immune responses in the gastrointestinal tract. It aims to explore how vagus nerve stimulation can modulate inflammation and tolerance, with potential therapeutic applications for gastrointestinal disorders.
In the gastrointestinal tract, the balance between activation of the mucosal immune system and tolerance should be tightly regulated to maintain immune homeostasis to prevent chronic inflammation and tissue damage.
Recently, the new concept was introduced that the vagus nerve plays an important role in modulating immune homeostasis as part of a so-called inflammatory reflex.
We provided evidence for this concept in the gastrointestinal tract and showed that vagus nerve stimulation (VNS) reduced…
KATHOLIEKE UNIVERSITEIT LEUVEN
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