CORDIS Project
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The project focuses on identifying and understanding the functions of effector proteins used by Chlamydia trachomatis to infect host cells. It aims to explore the type III secretion system and its role in bacterial virulence, contributing to the fight against infectious diseases.
Chlamydiales are a large group of highly related obligate intracellular bacteria that includes the human pathogens Chlamydia trachomatis and Chlamydophila pneumoniae. C. trachomatis is an agent of genital and ocular infections, and Cph. pneumoniae causes atypical pneumonias.
All Chlamydiae use a type III secretion (T3S) apparatus to translocate ~ 60-90 effector proteins into host cells.
These effectors are thought to play crucial roles in chlamydial dissemination but little is known about their…
INSTITUTO DE TECNOLOGIA QUIMICA E BIOLOGICA - UNIVERSIDADE NOVA DE LISBOA
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