CORDIS Project
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CHIPzophrenia seeks to create an advanced organ-on-chip system that allows precise control of the biochemical environment for studying brain disorders. It will investigate how nitrosative stress affects the blood-brain barrier and neuronal function, aiming to identify new treatment targets.
A well-controlled microenvironment is paramount for reproducible biomolecular studies.
Organs-on-chips are in-vitro cell culture systems that employ microfluidic and biomaterial engineering towards that goal.
They combine the advantages of animal models (physiological environment) with those of plastic-dish culture (human cells), and thereby hold exceptional promise in unraveling the biological processes that underlie health and disease.
Yet control over the biochemical environment remains poor.…
KUNGLIGA TEKNISKA HOEGSKOLAN
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