CORDIS Project
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This research aims to understand how left-right asymmetry in organisms arises from molecular chirality. By studying the actomyosin cortex in cells, it investigates the mechanisms driving chiral morphogenesis across different biological scales.
The aim of this grant is to understand how cellular, tissue-scale and organismal left-right asymmetry arisesfrom the chirality of molecular constituents.
In many instances the actomyosin cortex, a thin andmechanically active layer of dynamically cross-linked filaments and molecular motors at the surface of cells,drives the emergence of chiral morphogenetic events.
In the nematode Caenorhabditis elegans, mesoscalechiral active torques generated by this active layer establish the embryo’s left-rig…
TECHNISCHE UNIVERSITAET DRESDEN
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