CORDIS Project
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This project focuses on Chikungunya virus (CHIKV), aiming to develop antiviral compounds targeting the virus's replication proteins. By employing structural biology and drug screening techniques, it seeks to identify potential inhibitors to combat CHIKV infections effectively.
Chikungunya virus (CHIKV) is a medically important pathogen that affected millions of people around the world.
CHIKV infection causes high fever, intense joint pain and often leads to chronic virus-induced arthritis, thus there is a clear necessity to develop antiviral compounds capable of eliminating persisting virus.
CHIKV is an alphavirus from Togaviridae family with single-stranded positive-sense RNA genome, which replication is carried out by a complex of four viral non-structural (ns) prot…
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