CORDIS Project
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The project investigates the role of lipids in the process of cell division, specifically during cytokinesis. By combining chemical biology and imaging techniques, it aims to uncover the mechanisms behind membrane transport and lipid involvement, providing insights into normal cell division and its implications in dise…
Cytokinesis, the final step of cell division, has two crucial processes to achieve: equal sorting of cellular components between the daughter cells, and membrane ingression and closure.
Both processes strongly rely on membrane components and properties.
It is known that some lipids localize to the cleavage site and that membrane transport is required to relieve cortical tension during cytokinesis, which is necessary for the physical separation of cells.
However, the precise role and mechanism of…
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