CORDIS Project
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This project investigates the evolutionary origins of chemiosmosis by testing a hypothesis about ion transport mechanisms in early life forms. It aims to understand how energy production systems may have evolved in primitive cells.
All modern organisms feature chemiosmosis (ion-motive-force driven processes, including membrane transport and ATP production), and therefore the Last Common Universal Ancestor (LUCA) is believed to be chemiosmotic; although contradictorily.
As for chemiosmosis to happen, cells utilise membranes relatively impermeable to the coupling ion (H+ or Na+).
It has previously been shown that, theoretically, LUCA could drive chemiosmosis using a geo-chemical H+-gradient but only if it had a leaky membran…
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