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Chem2Sense aims to develop advanced biosensors by redesigning aptamers with flexible synthetic nucleotides and innovative sequencing techniques. This project focuses on creating high-affinity oligonucleotides that can detect various molecules, enhancing sensitivity and versatility for applications in health and environ…
Sensors have a vital importance on human life, detecting diseases or contaminants that endanger the environment. A widely pursued challenge has been to develop universal biosensors with the flexibility to detect molecules regardless of their size.
Antibodies have been used to fulfill this aim, but single-stranded oligonucleotides (aptamers) interact efficiently with targets and have also been proposed as an alternative.
However, aptamers lack the ability for versatile functionalization to tune a…
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