CORDIS Project
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This project investigates the biological mechanisms of aging by focusing on how changes in cell communication and signaling pathways contribute to age-related deterioration. It aims to identify reversible processes that could lead to interventions for maintaining youthful tissue function.
A major challenge in aging research is to distinguish which age-related alterations play a driving role and their interconnections.
Aging ultimately implies dysregulated transcription; yet, the identity of signaling cascades and transcription factors that control youthfulness and aging in adult tissues remains poorly understood.
Aging also entails maladaptive changes in how cells communicate with each other and their surrounding extracellular matrix (ECM).
Senolytics approaches have revealed the…
UNIVERSITA DEGLI STUDI DI PADOVA
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