CORDIS Project
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This research focuses on understanding how platelet surface receptors are regulated, which is crucial for blood clotting and various diseases. By employing advanced techniques, the project aims to discover small molecules that can modulate these receptors, potentially leading to new treatments for cardiovascular condit…
Signaling via platelet surface receptors is essential for maintaining hemostasis and thrombosis, and plays key roles in pathophysiological processes related to development, immune responses and cancer.
Despite their vital roles, important aspects of their regulation mechanisms remain unknown due to inherent flexibility and multilayered activation. I propose to embark upon a new approach to investigate the dynamical processes by which platelet receptors are regulated using a combination of x-ray…
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