CORDIS Project
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This project investigates a new therapeutic approach targeting metabolic syndrome by inhibiting the IDOL protein. It aims to develop small-molecule inhibitors that can address multiple associated health issues, including cardiovascular diseases and diabetes.
The prevalence of the MetS and associated co-morbidities including cardiovascular disease has reached epidemic proportions in the developed and developing world.
The cost of treating these conditions represents a substantial part of current European healthcare expenditure, and despite recent advances, treatments for MetS-associated lipid disorders are far from optimal; mainstay lipid-lowering treatments (e.g. statins) reduce cardiovascular risk by only ~30%, and recently-introduced PCSK9 inhibi…
ACADEMISCH MEDISCH CENTRUM BIJ DE UNIVERSITEIT VAN AMSTERDAM
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