CORDIS Project
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This project focuses on developing new methods for selectively modifying small and complex molecules through metal-catalyzed C–H bond functionalization. The aim is to create flexible and controllable reactions that can operate under mild conditions, enhancing the efficiency of chemical synthesis.
The capacity to selectively functionalise either small molecules or more complex structures represents a persistent and ever increasing challenge in chemical synthesis.
Transition metal catalysed coupling reactions have offered a revolutionary solution to the problem of selective derivatisation that has transformed the way we do synthesis over the last 30 years.
However, while these precise reactions almost always proceed as planned this is because you ‘pay up front’ for selectivity by using pre…
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