CORDIS Project
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This project aims to understand chromatin structure and its role in gene regulation. By studying nucleosome arrangements and chromatin remodeling, it seeks to uncover mechanisms that influence DNA accessibility and gene expression, which have implications for medical advancements.
DNA in higher organisms is organized in a nucleoprotein complex called chromatin.
The structure of chromatin is responsible for compacting DNA to fit within the nucleus and for governing its access in nuclear processes.
Epigenetic information is encoded chiefly via chromatin modifications.
Readout of the genetic code depends on chromatin remodeling, a process actively altering chromatin structure.
An understanding of the hierarchical structure of chromatin and of structurally based, remodeling m…
EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
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