CORDIS Project
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This project investigates the centrosome and cilium complex in animal cells, focusing on the role of centriolar satellites in maintaining their structure and function. It aims to understand how defects in these structures contribute to diseases like cancer and ciliopathies.
Centrosomes are the main microtubule-organizing centers of animal cells.
They influence the morphology of the microtubule cytoskeleton and function as the base of primary cilium, a nexus for important signaling pathways.
Structural and functional defects in centrosome/cilium complex cause a variety of human diseases including cancer, ciliopathies and microcephaly.
To understand the relationship between human diseases and centrosome/cilium abnormalities, it is essential to elucidate the biogenesi…
KOC UNIVERSITY
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