CORDIS Project
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This project develops a droplet microfluidics platform for ultra-high-throughput screening and sequencing of B-cells that produce therapeutic antibodies. It aims to link genotype and phenotype directly at single-cell resolution, enhancing antibody phenotyping while preserving original heavy-light chain pairing.
Tackling heterogeneous cell populations at single-cell resolution is becoming increasingly important in different branches of biology and biomedicine.
Many useful techniques have been developed to profile and even selectively purify single-cells, however, the demand for techniques with better analytical performance and improved high-throughput capabilities, remains very high.
Droplet microfluidics can fulfill this demand by bringing higher throughput, scalability and single molecule resolution t…
VILNIAUS UNIVERSITETAS
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