CORDIS Project
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This research explores the mechanisms of reprogramming somatic cells into pluripotent stem cells. By utilizing advanced genetic models and sequencing techniques, it aims to understand how to safely manipulate cell behavior for medical applications and disease research.
The generation of animals by nuclear transfer demonstrated that the epigenetic state of somatic cells could be reset to an embryonic state, capable of directing the development of a new organism.
The nuclear cloning technology is of interest for transplantation medicine, but any application is hampered by the inefficiency and ethical problems. A breakthrough solving these issues has been the in vitro derivation of reprogrammed Induced Pluripotent Stem “iPS” cells by the ectopic expression of def…
WEIZMANN INSTITUTE OF SCIENCE
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